matched controls 47 ± 3 ms).ĬOVID-19, SARS-CoV-2, Cardiovascular magnetic resonance, Myocarditis, Myocardial infarction, Myocardial oedema There was no evidence of diffuse fibrosis or oedema in the remote myocardium (T1: COVID-19 patients 1033 ± 41 ms vs. See page 1879 for the editorial comment on this article (doi: 10.1093/eurheartj/ehab145) IntroductionĬOVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global pandemic that continues to cause significant mortality and morbidity worldwide. 1 Although most cases are mild, a minority of patients sustain severe acute respiratory syndrome, the most frequent cause of death. Involvement of multiple organs including the heart has been reported 2, 3 and concern is growing that survivors may endure long-term sequelae, particularly after intensive care admission.Īcute respiratory infections and sepsis are often associated with elevated serum troponin levels, which are associated with mortality even after recovery. 4, 5 Similarly, elevated troponin is common in hospitalized COVID-19 patients 6–11 and is associated with adverse outcomes. 8, 10, 11 Patients with severe COVID-19 disease frequently have high rates of comorbidity associated with cardiac disease including diabetes, airways disease, and obesity. 13 Furthermore, concern is growing on the long-term sequalae in COVID-19 survivors, which represent an increasing number of patients as the pandemic progresses.ġ2 A variety of mechanisms responsible for troponin rise have been proposed including acute coronary syndromes, unmasking occult underlying cardiovascular disease, arrhythmias, myocarditis, or as part of a systemic inflammatory syndrome.
![osirix md 9.5 download osirix md 9.5 download](http://romestate.weebly.com/uploads/1/2/6/6/126683152/230475998_orig.png)
14Ĭardiovascular magnetic resonance (CMR) is useful to provide a diagnosis in patients with elevated troponin from unclear aetiology 14, 15 and is recommended by position statements. 16 Advances in multi-parametric CMR now include quantitative ischaemia assessment, and detailed tissue characterization including scar, diffuse fibrosis, and oedema.